Not just hands...
Dishidrotic Plamoplantar Eczema doesn't impact just hands...
I'm one of the unfortunate folks who has both involvement of both hands and feet. For me, it's really been a hard impact on my life... There are many things I no longer do, like hiking with the boy scouts, because I don't know when I might develop a flareup.
There are some times I wake up in the middle of night wracked in pain. I've been enduring this as a recurrent problem for over seven years.
Unfortunately, I don't have any advice for anyone else -- since I'm not having much luck myself. I've get some relief by keeping the amount of nickel low in my diet -- but that's not easy, especially when the lists of foods that are safe and to avoid vary dramatically from source to source.
I often get 3-6 months remission from a hydrocortisone injection.